Innovative dosage form
Orodispersable films, also known as oral thin strips or dissolvable strips, are a novel form of pharmaceutical and dietary supplement delivery system for its convenience, efficiency, and ease of use. These thin, flexible strips are designed to be placed on or under the tongue (sublingually) or along the inside of the cheek (buccally), where they rapidly dissolve, releasing the active ingredients directly into the bloodstream through the mucous membranes of the mouth. This method of delivery offers several advantages over traditional forms like tablets, capsules, and liquid solutions.
Composition & Structure
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The strips are made from a water-soluble polymer base. Commonly used polymers include pullulan, hydroxypropyl methylcellulose (HPMC), and carboxymethyl cellulose (CMC). These materials dissolve rapidly upon contact with saliva.
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The active ingredients are incorporated into the polymer matrix. These can range from pharmaceutical drugs to supplements like vitamins & minerals.
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Flavoring agents, sweeteners, and colorants are often added to improve the taste and appearance of the strips. Additionally, plasticizers like glycerin or propylene glycol are used to improve flexibility and prevent brittleness.
Oral dissolving thin strips can be used in a range of applications, from over-the-counter supplements for energy and hydration to prescription medications for pain relief, sleep aids, and more. The technology continues to evolve, expanding the range of possible active ingredients that can be effectively delivered through this innovative format.
Directions of use
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Step 1
The orodispersable film is placed on or underneath the tongue, or on the inside of the cheek
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Step 2
The orodispersable film will dissolve within seconds upon contact wth saliva
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Step 3
Active ingredients are delivered directly into the bloodstream for quick onset of action
Clinical Advantages
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Orodispersable films with lage surface area and quicker disintegration can help provide faster onset of action.
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Unlike liquid, tablet or capsule medications, there is high dosage precision with orodispersable films due to their immediate absorption.
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Convenient dosage form for administration to elderly patients and/or patients with chronic conditions.
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Orodispersable films are highly portable and dissolve instantly, posing zero risk of choking or the need for water.
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Orodispersable film allow for efficient taste masking and palatability.
Rapid Absorption
DEXSTRIPS are crafted to allow active ingredients to be absorbed quickly through the mucous membranes of the mouth, bypassing the gastrointestinal tract. This not only can help speed up the onset of action but also may enhance the bioavailability of the medication, ensuring maximum therapeutic effect.
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